Denana Miodragovic Ph.D.
Chemistry
Assistant Professor
Office:
Room BBH 212E
Phone:
(773) 442-5773
Email:
d-miodragovic@neiu.edu
Office Hours:
Email for availability
Country:
United States
CHEM 103, CHEM 108, CHEM 110, CHEM 211, CHEM 212, CHEM 391, CHEM 316, CHEM 406, CHEM 413
Research Interests
Medicinal Inorganic Chemistry and Bio-Inorganic Chemistry
Education
B.S., M.S., and Ph.D. in Chemistry (2003), University of Belgrade, Serbia
Doctoral thesis:
鈥淪yntheses and Stereochemistry of Cobalt(III) Complexes with Aromatic Amino Acids鈥
Adviser: Professor Slobodan Milosavljevic
Postdoctoral studies 鈥 Northwestern University, Evanston, USA
Adviser: Professor Thomas Vincent O鈥橦alloran
Project: Syntheses of inorganic anticancer agents based on the combination of platinum and arsenic drugs
Selected Publications
Miodragovi膰 DU, Merlino A, Swindell E, Marzo T., Bogachkov A., Ahn R., Abuhadba S, Ferraro G, Mazar AP, Messori L, and O鈥橦alloran TV, Arsenoplatin-1 is A Dual Pharmacophore Anti-Cancer Agent, JACS, 141 (16) (2019) 6453-6457.
Miodragovi膰 D, Swindell E.P, Waxali Z.S., Bogachkov A., and O鈥橦allorana T.V., Beyond Cisplatin: Combination Therapy with Arsenic Trioxide, Inorganica Chimica Acta, 496 (2019) 119030.
脨enana U. Miodragovi膰, Jeremy A. Quentzel, Josh W. Kurutz, Charlotte L. Stern, Richard W. Ahn, and Thomas O鈥橦alloran, Robust Structure and Activity of Aqueous Arsenous Acid-Platinum(II) Anticancer Complexes, Angew. Chem. In. Ed, 52 (2013) 10749-10752.
Swindell, Elden; Hankins, Patrick; Chen, Haimei; Miodragovi膰, 膼enana; O'Halloran, Thomas, Anticancer Activity of Small Molecule and Nanoparticulate Arsenic(III) Complexes", Inorg. Chem. (2013), 52, 12292-12 304.
Mini膰 Dragica M., Sumar-Ristovi膰 Maja T., Miodragovi膰 脨enana U., Andjelkovi膰 Katarina K., Poleti Dejan, Kinetics and mechanism of degradation of Co(II)-N-benzyloxycarbonylglycinato complex, J. Therm. Anal. Calorim. 7 (2012) 1167-1176.
Miodragovi膰 Djenana U., Jovanovi膰 Dragoljub, Bogdanovi膰 Goran A., Miti膰 Dragana, Andjelkovi膰 Katarina, Synthesis and crystal structures of 1,2,3,4-tetrahydro-9-aminoacridine tetrachlorozincate(II) monohydrate, J. Serb. Chem. Soc., 75 (2010) 1209-1218.
Sumar-Ristovi膰 Maja T., Mini膰 Dragica M., Poleti Dejan, Miodragovi膰 Zoran, Miodragovi膰 脨enana, Andjelkovic Katarina K., Thermal stability and degradation of Co(II), Cd(II), and Zn(II) complexes with N-benzyloxycarbonylglycinato ligand, J. Therm. Anal. Calorim. 102 (2010) 83-90.
Miti膰 D, Milenkovi膰 M, Milosavljevi膰 S, Go膽evac D, Miodragovi膰 Z, An膽elkovi膰 K and Miodragovi膰 D., Synthesis, characterization and antimicrobial activity of the Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine, Eur. J. Med. Chem. 44 (2009) 1537-1544.
Miodragovi膰 DU, Miti膰 DM, Miodragovi膰 ZM, Bogdanovi膰 GA, Vitnik 沤J, Vitorovi膰 MD, Radulovi膰 MD, Nastasijevi膰 BJ, Jurani膰 IO, Andjelkovi膰 KK,"Syntheses, characterization and antimicrobial activity of the first complexes of Zn(II), Cd(II) and Co(II) with N-benzyloxycarbonylglycine. X-ray crystal structure of the polymeric Cd(II) complex", Inorg. Chim. Acta 361 (2008) 86-94.
Miti膰 M, Miodragovi膰 DU, Sladi膰 DS, Vitnik 沤J, Miodragovi膰 ZM, Andjelkovi膰 KK, Radulovi膰 MD, Jurani膰 NO, " Synthesis, NMR, DFT and antimicrobial studies of the Zn(II) complexes with N-benzyloxycarbonyl-S-alanine" J. Serb. Chem. Soc. 73(2008) 813-822.
Miodragovi膰 DU, Bogdanovi膰 GA, Miodragovi膰 ZM, Radulovi膰 MD, Novakovi膰 SB, Kalu膽erovi膰 GN, Koz艂owski H, "Interesting coordination abilities of antiulcer drug famotidine and antimicrobial activity of drug and its cobalt(III) complex", J. Inorg. Biochem. 100 (2006) 1568-1574.
Miodragovi膰 ZM, Bogdanovi膰 GA, Kraj膷inovi膰 BB, Drakuli膰 BJ, Kusigerski VB, Miodragovi膰 DU, Spasojevi膰 VV, Hod啪i膰 IM, Jurani膰 IO, "Synthesis, structure and magnetic properties of the first copper(II) complex with an (E)-4-aryl-4-oxo-2-butenoato ligand", Inorganic Chemistry Communications 9 (2006) 1173鈥1177.
Miodragovi膰 DU, Miodragovi膰 ZM, Skala D, Malinar MJ and Mini膰 DM, "Mixed cobalt(III) complexes with aromatic amino acids and diamine. Part V. Thermal investigation of (1,2-diaminoethane)bis(S-tyrosinato)cobalt(III) complex diastereomers", Thermochimica Acta 436 (2005) 90-95.
Miodragovi膰 DU, Vitnik 沤J, Milosavljevi膰 SM, Malinar MJ, and Jurani膰 IO, "NH鈥ο Interactions Stabilize the Most-Hindered Rotamer of the (S)-Tyrosinato Side Group in Bis[(S)-tyrosinato](diamine)cobalt(III) Complexes: An NMR Spectroscopic and DFT Study, Eur. J. Inorg. Chem. (2005) 3172-3178.
Miodragovi膰 DU, Milosavljevi膰 SM, Malinar MJ, 膯elap MB, Todorovi膰 N, Jurani膰 N, "Mixed Cobalt(III) complexes with Aromatic amino Acids and Diamine. Part IV. Influence of Noncovalent Intra- and Interligand Interactions on Rotamer Population of the S-phenylalaninato and S-tyrosinato side groups in (1,2-Diaminoethane)bis(S-aminocarboxylato)cobalt(III) Complexes", Enantiomer 7 (2002) 375-382.
Bogdanovi膰 GA, Miodragovi膰 DU, Malinar MJ, "Mixed cobalt(III) complexes with aromatic amino acids and diamines. III. Absolute structure of 螖-trans(O)-(1,2-diaminoethane-k2N,N)bis(S-tyrosinato)cobalt(III)chloride tetrahydrate", Acta Cryst. C 58 (2002) 338-340.
Miodragovi膰 DU, Malinar MJ, Milosavljevi膰 SM, Zari膰 SD, Vu膷eli膰 D, 膯elap MB, "Synthesis and Absolute Configuration of Novel Mono- and Dinuclear Cobalt(III) Complexes containing S-phenylalanine", J. Coord. Chem. 55 (2002) 517-526.
Miodragovi膰 DU, Bogdanovi膰 GA, Milosavljevi膰 SM, Malinar MJ, 膯elap MB, Spasojevi膰-de Bire A, Macura S, Jurani膰 N, "Mixed Cobalt(III) Complexes with Aromatic Amino Acids and Diamine. Part II. Synthesis and Configuration of (1,2-diaminoethane)Bis(L-Tyrosinato)Cobalt(III) Complex Diastereomers. The Crystal Structure of 螖-C1-Cis(O)-Diastereomer", Enantiomer 6 (2001) 299-308.
Malinar MJ, Miodragovi膰 DU, 膯elap MB, Vukovi膰 D, Zakrzewska JS, Vu膷eli膰 D, "Mixed Cobalt(III) complexes with S-tyrosine and 1,3-Diaminopropane", Enantiomer 3 (1998) 349-356.
Malinar MJ, Miodragovi膰 DU, 膯elap MB, Vukovi膰 D, Zakrzewska JS, Vu膷eli膰 D, "Mono- and dinuclear cobalt(III) complexes with S-tyrosine", J. Coord. Chem. 42 (1997) 343-351.
Selected Exhibitions
PRESENTATIONS
Ninth Annual Student Center for Science Engagement Research Symposium, NEIU, November 16, 2018.
Seventh Annual Student Center for Science Engagement Research Symposium, NEIU, November 18, 2016.
Fifth Annual Research & Creative symposium, 天天吃瓜, Chicago, November 14, 2014.
天天吃瓜 Fourth Annual Research & Creative Activity Symposium, Chicago, November, 25, 2013.
SMASH 2012, Providence, Rhode Island, September 9th-12th, 2012.
9th European Biological Inorganic Chemistry Conference, Wroclaw, Poland, September 2-6, 2008.
2nd European Conference on Chemistry for Life Sciences, Wroclaw, Poland, September 4-8, 2007.
2nd European Conference on Chemistry for Life Sciences, Wroclaw, Poland, September 4-8, 2007,
5th ICOSECS, Ohrid, September 10-14, 2006.
1st European Chemistry Congress, Budapest, Hungary, August 27-31, 2006.
X International Symposium on Bioinorganic Chemistry, Szklarska Poreba, Poland, September 20-25, 2005.
X International Symposium on Bioinorganic Chemistry, Szklarska Poreba, Poland, September 20-25, 2005.
4th International Conference of the Chemical Societies of the South-East European Countries on Chemical Sciences in Changing Times: Visions, Challenges and Solutions, Belgrade, Serbia and Montenegro, July 18-21, 2004.
7th International Conference on Fundamental and Applied Aspects of Physical Chemistry, Belgrade, Yugoslavia, September 21-23, 2004.
7th International Conference on Fundamental and Applied Aspects of Physical Chemistry, Belgrade, Yugoslavia, September 21-23, 2004.
Fourth Yugoslav Materials Research Society Conference 虏YUCOMAT虏, Herceg Novi,Yugoslavia, September 10-14, 2001.
5th International Conference on Fundamental and Applied Aspects of Physical Chemistry, Belgrade, Yugoslavia, September 2000.
1st International Conference of the Chemical Societies of the South-East European Countries, Halkidiki, Greece, June 1-4, 1998.
6th International Conference on Circular Dichroism, Pisa, Italy, September 21-24,1997.
6th International Conference on Circular Dichroism, Pisa, Italy, September 21-24,1997.
Background
Professional Experience
Assistant Professor, 天天吃瓜 (2024-present)
Instructor, 天天吃瓜 (2013-2024)
Adjunct Faculty, 天天吃瓜 (2011-2012)
Visiting Scholar, Northwestern University (2012-present)
Adjunct Professor of Chemistry, Wilbur Wright College (2012-2013)
Research Associate, Northwestern University (2009-2011)
Sabbatical, Northwestern University (2008-2009)
Assistant Professor, Faculty of Chemistry, University of Belgrade (2003-2009)
Additional Information
AWARDS
Instructor Excellence Award 2020
Educational Leave Award 2019
Student Choice Award, NEIU, 2016
Research Award, Ministry of Science of the Republic of Serbia, 2004
PATENTS
Miodragovic DU and O鈥橦alloran TV, US Patent No. 10118938, November 6, 2018
Miodragovic DU and O鈥橦alloran TV, US Patent No. 9725475, August 8, 2017.
Miodragovic DU and O鈥橦alloran TV, US Patent No. 9499574, November 22, 2016.
GRANTS (Co-researcher)
1UO1CA151461-01- "Tumor Targeted Nanobins for the Treatment of Metastatic Breast and Ovarian Cancer" (2009-2011).
W.M. Keck Foundation Grant, "The Inorganic Signature of Life: Signaling Pathways in the Mammalian Oocyte"(2008 - 2009).
Synthesis, characterization and activity of organic and coordination compounds, and their appliance in (bio)nanotechnology (2005-2010).
Synthesis and structure of potentially anti-cancer platinum(IV) complexes and simmilar coordination compounds (2002-2005).
Physico-chemical, structural and biological investigation of complex compounds (2002-2005).
PROFESSIONAL SERVICES
Reviewer for the Journal of Serbian Chemical Society (from 2019)
The representative of Serbia in European Association for Chemical and Molecular Science, Division of Chemistry in Life Sciences (2006-2010)
Peer reviewer for: Inorganica Chimica Acta, Spectrochimica Acta Part A, Bioinorganic Chemistry and Application, The Arabian Journal for Science and Engineering (2003-2008)
MEMBERSHIP
American Chemical Society 2010-present
Serbian Chemical Society 2003-2008